![]() ![]() Synaptic dysfunction caused by soluble β-amyloid peptide (Aβ) is a hallmark of early-stage Alzheimer's disease (AD), and is tightly linked to cognitive decline. We reveal that rice roots are responsive to changes in soil water conditions and that rice plants differentially adapts the dynamics of photosynthates translocation to crown roots and seminal roots depending on soil conditions. We suggest that when rice plant experiencing drought is re-irrigated from the bottom of pot, the destination of 11C-photosynthates translocation immediately switches from seminal root to crown roots. The photosynthates translocation to seminal roots immediately stopped after rewatering then increased significantly in crown roots. ![]() The results revealed that when soil is drier, 11C-photosynthates mainly translocated to the seminal roots, likely to promote elongation of the root with the aim of accessing water stored in the lower soil layers. The short half-life of 11C (20.39 min) allowed us to perform multiple experiments using the same plant, and thus photosynthate translocation was visualized as the same plant was subjected to drought stress and then re-irrigation for recovery. To visualize the distribution of photosynthates in the root system of rice plants under drought stress and recovery from drought stress, we combined X-ray computed tomography (CT) with open type positron emission tomography (OpenPET) and positron-emitting tracer imaging system (PETIS) with 11C tracer. Roots are directly exposed to changes in the soil water condition, and their responses to these environmental changes are driven by photosynthates. To enhance drought resistance, elucidating the mechanisms by which rice plants adapt to intermittent drought stress that may occur in the field is an important requirement. Rice is susceptible to abiotic stresses such as drought stress. Pretreatment of NLR could act as an independent prognostic indicator and help inform treatment strategies for older patients with OSCC. A high NLR was associated with BSI and resistance to curative-intent treatment. Moreover, a high NLR was an independent risk factor associated with disease-free survival. Ever betel nut chewing, hypoalbuminemia, and advanced tumor stage were associated with shorter overall survival. BSI was not significantly associated with survival status. ![]() A preoperative high neutrophil-to-lymphocyte ratio (NLR) was a significant independent risk factor for BSI. Of the 235 elderly patients, 27 presented with BSI episodes. Retrospective data were collected from 235 patients who were newly diagnosed with OSCC, were aged ≥ 65 years, had undergone curative-intent treatment, and were classified into either the BSI group or the no-BSI group within 6 months after surgery and/or adjuvant therapy initiation. This study aimed to investigate the association of pretreatment sarcopenia, nutritional status, comorbidities, and blood-based inflammation prognostic biomarkers in bloodstream infection (BSI) with survival status in elderly patients with OSCC. Patients with oral cavity squamous cell carcinoma (OSCC) undergoing curative-intent treatment may become immunocompromised. OsiriX is provided free of charge under the GNU open-source licensing agreement at. This ensures that all new developments in image processing that could emerge from other academic institutions using these libraries can be directly ported to the OsiriX program. The processing and image rendering tools of the software are based on the open-source libraries ITK and VTK. ![]() The program can easily be adapted for very specific tasks that require a limited number of functions, by adding and removing tools from the program's toolbar and avoiding an overwhelming number of unnecessary tools and functions. An interactive jog-wheel device widely used in the video and movie industry was implemented to allow users to navigate in the different dimensions of an image set much faster than with a traditional mouse or on-screen cursors and sliders. In the design of the software special attention was given to adapt the user interface to the specific and complex tasks of navigating through large sets of image data. It also benefits from the extremely fast and optimized 3D graphic capabilities of the OpenGL graphic standard widely used for computer games optimized for taking advantage of any hardware graphic accelerator boards available. The software is developed in Objective-C on a Macintosh platform under the MacOS X operating system using the GNUstep development environment. A multidimensional image navigation and display software was designed for display and interpretation of large sets of multidimensional and multimodality images such as combined PET-CT studies. ![]()
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